P748Afterload-induced TRIF-dependent signaling promotes fibrosis but not cardiomyocyte hypertrophy
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DOI: 10.1093/eurheartj/ehz747.0350
Abstract: Pressure overload dependent cardiac remodeling is characterized by a continuous functional loss of cardiomyocytes, cardiomyocyte hypertrophy, cell death and fibrosis. The relevance of the MyD88- and NFκB-independent inflammatory TRIF (TIR-domain-containing adapter protein inducing IFN-β) signaling… read more here.
Keywords: cardiomyocyte hypertrophy; hypertrophy; trif mice; trif dependent ... See more keywords
TIR-Domain-Containing Adapter-Inducing Interferon-β (TRIF)-Dependent Antiviral Responses Protect Mice against Ross River Virus Disease
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DOI: 10.1128/mbio.03363-21
Abstract: RRV has been prevalent in the South Pacific region for decades and causes substantial economic and social costs. Though RRV is geographically restricted, a number of other alphaviruses have spread globally due to expansion of… read more here.
Keywords: rrv; type ifn; disease; trif mice ... See more keywords