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Published in 2017 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2017.03.040
Abstract: Abstract 2-Amino-4 H -pyrane derivatives are nowadays well recognized as valuable scaffold in drug discovery. In this manuscript a new and improved multicomponent process for the chemical synthesis of the title compounds is described. β-Dicarbonyl…
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Keywords:
amino;
ytterbium triflate;
triflate promoted;
solvent free ... See more keywords
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Published in 2025 at "Organic letters"
DOI: 10.1021/acs.orglett.5c00011
Abstract: Sulfonamides are prevalent functional groups represented in both natural and pharmaceutical products. The synthesis of sulfonamides is often straightforward when using nucleophilic amines and electrophilic sulfonyl chlorides. When reactivity challenges arise for nontraditional substrates, harsh…
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Keywords:
triflate promoted;
triflate;
silyl triflate;
promoted sulfonylations ... See more keywords