Controllable access to trifluoromethyl-containing indoles and indolines: palladium-catalyzed regioselective functionalization of unactivated alkenes with trifluoroacetimidoyl chlorides
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DOI: 10.1039/d2sc00546h
Abstract: The synthesis of diverse products from the same starting materials is always attractive in organic chemistry. Here, a palladium-catalyzed substrate-controlled regioselective functionalization of unactivated alkenes with trifluoroacetimidoyl chlorides has been developed, which provides a direct… read more here.
Keywords: functionalization unactivated; alkenes trifluoroacetimidoyl; palladium catalyzed; trifluoroacetimidoyl chlorides ... See more keywords
Construction of trifluoromethyl-containing heterocycles from trifluoroacetimidoyl chlorides and derivatives.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00836c
Abstract: Recent advances in the direct synthesis of trifluoromethyl-containing heterocycles from trifluoroacetimidoyl chlorides (TFAICs) and derivatives, including trifluoroacetimidohydrazides (TFAIHs) and CF3-imidoyl sulfoxonium ylides (TFISYs), are systematically summarized and discussed. The cascade annulation reactions of trifluoromethyl-containing synthons… read more here.
Keywords: heterocycles trifluoroacetimidoyl; trifluoromethyl containing; construction trifluoromethyl; trifluoroacetimidoyl chlorides ... See more keywords