Oxidative Trifluoroacetoxylation of 1°, 2°, and 3° Benzylic C(sp3)-H Bond Donors Using N-Trifluoroacetoxyquinuclidinium Salts under Photoredox Catalysis.
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DOI: 10.1021/acs.orglett.2c02946
Abstract: N-Trifluoroacetoxyquinuclidinium trifluoroacetate was prepared in situ from quinuclidine N-oxide and (CF3CO)2O. Except for some electron-poor substrates, this reagent allows for the high-yielding oxidative trifluoroacetoxylation of 1°, 2°, and 3° benzylic C-H bonds under photocatalytic conditions.… read more here.
Keywords: benzylic sp3; trifluoroacetoxyquinuclidinium; trifluoroacetoxylation; oxidative trifluoroacetoxylation ... See more keywords