Copper(II)-Catalyzed Direct C-H Trifluoroethylation of Heteroarenes.
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DOI: 10.1021/acs.orglett.2c00245
Abstract: Trifluoroethyl (CH2CF3) is an important functional group in many pharmaceutical and agrochemical compounds. Herein, we report an efficient method for the copper-catalyzed direct trifluoroethylation of heteroarenes. The reaction exhibited good compatibility to various substrates, and… read more here.
Keywords: trifluoroethylation heteroarenes; direct trifluoroethylation; copper catalyzed; catalyzed direct ... See more keywords