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Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04214
Abstract: A new class of trifluoromethyl building blocks─2-trifluoromethyl allyl chlorides─have been obtained through a photoredox-catalyzed chlorotrifluoromethylation of aryl allenes. The reaction proceeded in a regio- and stereoselective manner. A trifluoromethylated analog of the flunarizine drug was…
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Keywords:
trifluoromethyl building;
photoredox catalyzed;
catalyzed chlorotrifluoromethylation;