Modular Access to 2-(Trifluoromethyl)pyrazolo[1,5-a]pyridines and Their Benzo Analogues through a Copper(I)-Catalyzed Radical Annulation.
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DOI: 10.1021/acs.orglett.2c02500
Abstract: A mechanistically distinctive copper-catalyzed radical annulation to valuable 2-(trifluoromethyl)pyrazolo[1,5-a]pyridines and their benzo analogues has been described for the first time. Notably, the newly developed complementary process allows the synthesis of 4- or 6-substituted target molecular… read more here.
Keywords: pyridines benzo; catalyzed radical; radical annulation; pyrazolo pyridines ... See more keywords