Two Catalytic Annulation Modes via Cu-Allenylidenes with Sulfur Ylides that Are Dominated by the Presence or Absence of Trifluoromethyl Substituents
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DOI: 10.1016/j.isci.2020.100994
Abstract: Summary We disclose the Cu-catalyzed enantioselective synthesis of 3-methyl-3-propargyl-indolines, which contain a quaternary stereogenic carbon center, via the decarboxylative [4 + 1] annulation of 4-methyl-4-propargyl-benzoxazinanones with variety of sulfur ylides. The reaction proceeds predominantly through… read more here.
Keywords: annulation; allenylidene intermediates; sulfur ylides; attack allenylidene ... See more keywords
Altering the Site of Electron Abstraction in Cobalt Corroles via meso-Trifluoromethyl Substituents.
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DOI: 10.1021/acs.inorgchem.3c00187
Abstract: A mono-DMSO cobalt meso-CF3 corrole, formulated as (CF3)3CorCo(DMSO), where (CF3)3Cor is the trianion of 5,10,15-tris(trifluoromethyl)corrole, was synthesized and characterized as to its spectral and electrochemical properties in nonaqueous media with a focus on its coordination… read more here.
Keywords: electron abstraction; cobalt; chemistry; trifluoromethyl substituents ... See more keywords
Synthesis and Cytotoxic Evaluation of Fluoro and Trifluoromethyl Substituents Containing Novel Naphthoquinone-Fused Podophyllotoxins
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DOI: 10.1177/1934578x221133196
Abstract: A series of novel naphthoquinone-fused podophyllotoxins containing fluoro and trifluoromethyl substituents were synthesized in a medium with good yields using two different synthetic approaches: microwave-assisted four-component reactions of 2-hydroxy-1,4-naphthoquinone, tetronic acid, fluorinated arylaldehydes, and ammonium… read more here.
Keywords: naphthoquinone fused; novel naphthoquinone; fluoro trifluoromethyl; trifluoromethyl substituents ... See more keywords