3-Functional substituted 4-trifluoromethyl tetrahydrothiophenes via [3 + 2]-cycloaddition reactions
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DOI: 10.1080/17415993.2019.1633326
Abstract: New 4-(trifluoromethyl)tetrahydrothiophenes containing an ester, sulfone, sulfoximine, sulfonamide, or phosphonate moiety at position 3 were synthesized by 1,3-dipolar [3 + 2]-cycloaddition reactions of 3,3,3-trifluoropropene derivatives and thiocarbonyl ylide generated in situ from chloromethyl trimethylsilylmethyl sulfide. GRAPHICAL ABSTRACT read more here.
Keywords: tetrahydrothiophenes via; cycloaddition reactions; functional substituted; substituted trifluoromethyl ... See more keywords