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Published in 2022 at "Organic letters"
DOI: 10.1021/acs.orglett.2c00148
Abstract: Here, we report a nickel-catalyzed enantioconvergent hydroalkylation of olefins with trifluoromethyl-containing α-alkyl halides for the synthesis of enantioenriched trifluoromethylated alkanes. This reaction employs readily available and bench-stable alkenes as alkyl coupling partners, featuring mild conditions,…
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Keywords:
diverse synthesis;
hydroalkylation;
nickel catalyzed;
trifluoromethylated alkanes ... See more keywords