Trifluoromethylation of Secondary Nitroalkanes.
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DOI: 10.1021/acs.orglett.7b01196
Abstract: Using a commercially available Umemoto's reagent, the metal-free trifluoromethylation of nitroalkanes is now possible. This method provides a general, high-yielding synthesis of α-(trifluoromethyl)nitroalkanes. The quaternary α-(trifluoromethyl)nitroalkanes obtained from this transformation can be elaborated to a… read more here.
Keywords: secondary nitroalkanes; trifluoromethylation secondary;