Cu and Hydroquinone for the Trifluoromethylation of Unprotected Phenols
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DOI: 10.1002/ejoc.201801111
Abstract: Fluorination and trifluoromethylation are indispensable tools in the preparation of modern pharmaceuticals and APIs. Herein we present a concept for the introduction of a trifluoromethyl group into unprotected phenols employing catalytic copper(I) iodide and hydroquinone,… read more here.
Keywords: hydroquinone trifluoromethylation; trifluoromethylation; trifluoromethylation unprotected; chemistry ... See more keywords