Morphology of the trigeminal ganglion: anatomical structures related to trigeminal radiofrequency rhizotomy
Sign Up to like & getrecommendations! Published in 2022 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-022-05160-7
Abstract: Trigeminal neuralgia is the most common example of craniofacial neuralgia. Its etiology is unknown and is characterized by severe episodes of paroxysmal pain. The trigeminal ganglion and its adjacent anatomical structures have a complex anatomy.… read more here.
Keywords: radiofrequency rhizotomy; trigeminal ganglion; ganglion; anatomical structures ... See more keywords
The P2Y14 receptor in the trigeminal ganglion contributes to the maintenance of inflammatory pain
Sign Up to like & getrecommendations! Published in 2019 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2019.104567
Abstract: P2Y purinergic receptors expressed in neurons and satellite glial cells (SGCs) of the trigeminal ganglion (TG) contributes to inflammatory and neuropathic pain. P2Y14 receptor expression is reported in the spinal cord, dorsal root ganglion (DRG),… read more here.
Keywords: p2y14 receptor; receptor; pain; trigeminal ganglion ... See more keywords
Connexin 43 contributes to temporomandibular joint inflammation induced-hypernociception via sodium channel 1.7 in trigeminal ganglion
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.134301
Abstract: We previously demonstrated that sodium channel 1.7 (Nav1.7) in trigeminal ganglion (TG) was a critical factor in temporomandibular joint (TMJ) inflammation-induced hypernociception, but the mechanism underlying inflammation-induced upregulation of Nav1.7 remained unclear. Glial-neuron interaction plays… read more here.
Keywords: induced hypernociception; hypernociception; sodium channel; inflammation ... See more keywords
Trigeminal ganglion metastasis of renal clear cell carcinoma: Cases reports and literature review.
Sign Up to like & getrecommendations! Published in 2019 at "World neurosurgery"
DOI: 10.1016/j.wneu.2019.04.230
Abstract: The trigeminal ganglion is an atypical site for metastasis, especially for renal clear cell carcinoma (RCC). We report two clinical cases of 66- and 58-year-old men with trigeminal symptoms. Both patients had a history of… read more here.
Keywords: renal clear; cell carcinoma; metastasis; clear cell ... See more keywords
A TRPM7 mutation linked to familial trigeminal neuralgia: Omega current and hyperexcitability of trigeminal ganglion neurons
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2119630119
Abstract: Significance This study explores the potential pathogenic effects of a novel mutation of TRPM7 channel (A931T) identified in a 73-year-old man affected by familial trigeminal neuralgia. We show that A931T results in an abnormal Na+… read more here.
Keywords: familial trigeminal; trigeminal neuralgia; omega current; mutation ... See more keywords
Assigning transcriptomic class in the trigeminal ganglion using multiplex in situ hybridization and machine learning.
Sign Up to like & getrecommendations! Published in 2020 at "Pain"
DOI: 10.1097/j.pain.0000000000001911
Abstract: Single cell sequencing has provided unprecedented information about the transcriptomic diversity of somatosensory systems. Here we describe a simple and versatile in situ hybridization (ISH) based approach for mapping this information back to the tissue.… read more here.
Keywords: machine learning; class; transcriptomic class; approach ... See more keywords
Postinfection Metabolic Reprogramming of the Murine Trigeminal Ganglion Limits Herpes Simplex Virus-1 Replication
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.02194-22
Abstract: The more severe ocular pathologies associated with HSV-1 infection are significant vision loss, ocular morbidity, and herpetic keratitis. The current clinical landscape lacks curative drugs and vaccines against HSV-1, a heavy burden associated with this… read more here.
Keywords: infection; simplex virus; hsv infection; herpes simplex ... See more keywords
Dexmedetomidine Inhibits Voltage-Gated Sodium Channels via α2-Adrenoceptors in Trigeminal Ganglion Neurons
Sign Up to like & getrecommendations! Published in 2018 at "Mediators of Inflammation"
DOI: 10.1155/2018/1782719
Abstract: Dexmedetomidine, an α2-adrenoceptor agonist, is widely used as a sedative and analgesic agent in a number of clinical applications. However, little is known about the mechanism by which it exerts its analgesic effects on the… read more here.
Keywords: voltage gated; via adrenoceptors; gated sodium; sodium channels ... See more keywords
Characterization of Acetylation of Histone H3 at Lysine 9 in the Trigeminal Ganglion of a Rat Trigeminal Neuralgia Model
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/1300387
Abstract: Trigeminal neuralgia (TN) is a chronic neuropathic pain disorder characterized by spontaneous and elicited paroxysms of electric-shock-like or stabbing pain in a region of the face. The epigenetic regulation of TN is still obscure. In… read more here.
Keywords: characterization acetylation; trigeminal neuralgia; model; trigeminal ganglion ... See more keywords
Corrigendum to “Nav1.7 via Promotion of ERK in the Trigeminal Ganglion Plays an Important Role in the Induction of Pulpitis Inflammatory Pain”
Sign Up to like & getrecommendations! Published in 2022 at "BioMed Research International"
DOI: 10.1155/2022/9826502
Abstract: [This corrects the article DOI: 10.1155/2019/6973932.]. read more here.
Keywords: nav1 via; trigeminal ganglion; promotion erk; via promotion ... See more keywords
Fluorescent Labeling and 2-Photon Imaging of Mouse Tooth Pulp Nociceptors
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Dental Research"
DOI: 10.1177/0022034517740577
Abstract: Retrograde fluorescent labeling of dental primary afferent neurons (DPANs) has been described in rats through crystalline fluorescent DiI, while in the mouse, this technique was achieved with only Fluoro-Gold, a neurotoxic fluorescent dye with membrane… read more here.
Keywords: photon; dii; fluorescent labeling; mouse ... See more keywords