Estrogen modulation of the pronociceptive effects of serotonin on female rat trigeminal sensory neurons is timing- and dosage-dependent and requires estrogen receptor alpha.
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DOI: 10.1097/j.pain.0000000000002604
Abstract: ABSTRACT The role of the major estrogen estradiol (E2) on orofacial pain conditions remains controversial with studies reporting both a pronociceptive and antinociceptive role of E2. E2 modulation of peripheral serotonergic activity may be one… read more here.
Keywords: orofacial pain; modulation; trigeminal sensory; pain ... See more keywords
Trigeminal sensory modulatory effects of galcanezumab and clinical response prediction.
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DOI: 10.1097/j.pain.0000000000002614
Abstract: ABSTRACT Galcanezumab, a monoclonal antibody against calcitonin gene-related peptide, is an emerging migraine preventative. We hypothesized that the preventive effects are conveyed via modulation of somatosensory processing and that certain sensory profiles may hence be… read more here.
Keywords: clinical response; trigeminal sensory; sensory modulatory; modulatory effects ... See more keywords
Photoactivation of olfactory sensory neurons does not affect action potential conduction in individual trigeminal sensory axons innervating the rodent nasal cavity
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DOI: 10.1371/journal.pone.0211175
Abstract: Olfactory and trigeminal chemosensory systems reside in parallel within the mammalian nose. Psychophysical studies in people indicate that these two systems interact at a perceptual level. Trigeminal sensations of pungency mask odour perception, while olfactory… read more here.
Keywords: olfactory; sensory neurons; olfactory sensory; trigeminal sensory ... See more keywords