Multisite Labeling of Proteins Using the Ligand-Directed Reactivity of Triggerable Michael Acceptors.
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DOI: 10.1021/acs.bioconjchem.3c00155
Abstract: Targeted modification of endogenous proteins without genetic manipulation of protein expression machinery has a range of applications from chemical biology to drug discovery. Despite being demonstrated to be effective in various applications, target-specific protein labeling… read more here.
Keywords: triggerable michael; ligand directed; ligand; reactivity ... See more keywords