Palladium-Catalyzed Imidoylation-Triggered [2 + 2 + 1] Cyclization of Internal Alkyne with Isocyanides.
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DOI: 10.1021/acs.orglett.0c02019
Abstract: In this work, a palladium-catalyzed [2 + 2 + 1] cyclization of internal alkynes with double isocyanides is described. This facile procedure is efficient for synthesizing various pyrrolo[3,2-c]quinolin-2-amines. The reaction worked well with a broad… read more here.
Keywords: cyclization internal; imidoylation triggered; cyclization; palladium catalyzed ... See more keywords
1,5-Hydride-Shift-Triggered Cyclization for the Synthesis of Unsymmetric Julolidines
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DOI: 10.1055/a-1559-2728
Abstract: Directly accessible 8-substituted tetrahydroquinolines undergo 1,5-hydride-shift-triggered cyclization to provide difficult to access julolidine derivatives in yields of 21–98% under scandium(III) triflate catalysis. Additionally, the scope of the reaction, several follow-up transformations and a remarkable side… read more here.
Keywords: shift triggered; hydride shift; triggered cyclization; synthesis unsymmetric ... See more keywords