μ Opioid Receptor-Triggered Notch-1 Activation Contributes to Morphine Tolerance: Role of Neuron–Glia Communication
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DOI: 10.1007/s12035-019-01706-6
Abstract: The development of analgesic tolerance to opioids is an important limitation in the management of chronic pain. Spinal cord glial cell activation appears to play a pivotal role in the development and maintenance of opioid… read more here.
Keywords: tolerance; triggered notch; role; activation ... See more keywords