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Monacolin K Induces Apoptosis of Human Glioma U251 Cells by Triggering ROS-Mediated Oxidative Damage and Regulating MAPKs and NF-κB Pathways.

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Published in 2023 at "ACS chemical neuroscience"

DOI: 10.1021/acschemneuro.3c00104

Abstract: Monacolin K (MK), a polyketo secondary metabolic compound of the mold genus Monascus, can promote the apoptosis of malignant cancer cells, possessing potential antitumor properties. However, its mechanism of action on gliomas remains unclear. Here,… read more here.

Keywords: cells triggering; human glioma; u251 cells; triggering ros ... See more keywords