Targeting triglyceride metabolism for colorectal cancer prevention and therapy.
Sign Up to like & getrecommendations! Published in 2021 at "Current drug targets"
DOI: 10.2174/1389450122666210824150012
Abstract: BACKGROUND Triglycerides (TG) are one of the major constituents of body fat and energy reservoir, which consist of an ester derived from glycerol and three free fatty acids. TG lipase, monoacylglycerol lipase, fatty acid synthase,… read more here.
Keywords: metabolism; triglyceride metabolism; pathway mediators; colorectal cancer ... See more keywords
Effects of Alirocumab on Triglyceride Metabolism: A Fat-Tolerance Test and Nuclear Magnetic Resonance Spectroscopy Study
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10010193
Abstract: Background: PCSK9 antibodies strongly reduce LDL cholesterol. The effects of PCSK9 antibodies on triglyceride metabolism are less pronounced. The present study aimed to investigate in detail the effects of alirocumab on triglycerides, triglyceride-rich lipoproteins, and… read more here.
Keywords: triglyceride metabolism; spectroscopy; pcsk9; treatment ... See more keywords
Apolipoprotein A5 regulates intracellular triglyceride metabolism in adipocytes
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DOI: 10.3892/mmr.2017.7461
Abstract: It has previously been demonstrated that apolipoprotein A5 (apoA5) can be internalized by human adipocytes and significantly decreases intracellular triglyceride content. In the present study, endocytosis of apoA5 by adipocytes under different conditions, and the… read more here.
Keywords: metabolism adipocytes; triglyceride metabolism; present study; intracellular triglyceride ... See more keywords