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   Articles with "triglyceride transfer" as a keyword



Identification of antisense transcripts of the microsomal triglyceride transfer protein genes in humans and mice.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.07.069

Abstract: Microsomal triglyceride transfer protein (MTTP) is essential for the assembly and secretion of apoB-containing lipoproteins. Here, we report the presence of genes on the anti-sense strands of the human MTTP and mouse Mttp genes. The… read more here.

Keywords: triglyceride transfer; transfer protein; mttp; mttp as1 ... See more keywords

The crystal structure of human microsomal triglyceride transfer protein

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recommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.1903029116

Abstract: Significance This study provides a structure for microsomal triglyceride transfer protein, a key protein in lipid metabolism and transport. Microsomal triglyceride transfer protein is linked to a human disease state, abetalipoproteinemia. The structure helps us… read more here.

Keywords: transfer protein; triglyceride transfer; structure; microsomal triglyceride ... See more keywords

ATG2 is a triglyceride transfer protein.

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recommendations! Published in 2025 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2517469122

Abstract: Bridge-like lipid transfer proteins (BLTPs) are established to function in phospholipid transport between bilayers at organelle-organelle contact sites. However, the BLTP ATG2A also associates with lipid droplets in cells, which present a unique phospholipid monolayer… read more here.

Keywords: atg2 triglyceride; transfer protein; triglyceride transfer; transfer ... See more keywords

Regulating microsomal triglyceride transfer protein with natural products for the treatment of hyperlipidaemia

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recommendations! Published in 2024 at "Natural Product Research"

DOI: 10.1080/14786419.2023.2300031

Abstract: Abstract Hyperlipidaemia, characterised by elevated levels of lipids, particularly LDL-C, is a significant risk factor for atherosclerotic cardiovascular disease. While synthetic inhibitors of microsomal triglyceride transfer protein (MTP) have shown potential in lowering LDL-C, they… read more here.

Keywords: transfer protein; natural products; triglyceride transfer; hyperlipidaemia ... See more keywords