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   Articles with "trigonelline" as a keyword



Trigonelline inhibits caspase 3 to protect &bgr; cells apoptosis in streptozotocin‐induced type 1 diabetic mice

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recommendations! Published in 2018 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2018.08.025

Abstract: Abstract As a main active ingredient of Fenugreek, trigonelline has protective efficiency on type 2 diabetes and diabetic peripheral neuropathy in rats. This study investigates the protection of trigonelline on hyperglycemia, &bgr; cell apoptosis, and… read more here.

Keywords: trigonelline; bgr; type diabetic; bgr cells ... See more keywords

Iron and zinc oxide nanoparticles: An efficient elicitor to enhance trigonelline alkaloid production in hairy roots of fenugreek

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recommendations! Published in 2021 at "Industrial Crops and Products"

DOI: 10.1016/j.indcrop.2021.113240

Abstract: Abstract Fenugreek (Trigonella foenum-graecum L.) is a rich source of important medicinal metabolites. This plant belongs to the Fabaceae family that grows anywhere around the world. It is extensively used in medicine and as a… read more here.

Keywords: production; oxide nanoparticles; hairy roots; trigonelline ... See more keywords

Trigonelline: An alkaloid with anti-degranulation properties.

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recommendations! Published in 2019 at "Molecular immunology"

DOI: 10.1016/j.molimm.2019.12.020

Abstract: Trigonelline, one of the alkaloids contained in coffee, is important not only as one of the constituents of aroma and flavor in coffee but also as a useful source of nutrition. Its anti-microbial, anti-carcinogenic, and… read more here.

Keywords: degranulation; trigonelline; anti degranulation; degranulation effect ... See more keywords

Does trigonelline help skin tone? Molecular docking studies of trigonelline on the human tyrosinase, formulation, optimization, and characterization of an emulgel‐containing Trigonella foenum‐graecum L. fenugreek standardized hydroalcoholic extract

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recommendations! Published in 2022 at "Journal of Cosmetic Dermatology"

DOI: 10.1111/jocd.15453

Abstract: This study aimed to perform molecular docking studies to identify possibilities of the inhibitory potential of the trigonelline present in fenugreek seeds on the human tyrosinase, standardize fenugreek extract, formulate, and characterize an emulgel‐containing fenugreek… read more here.

Keywords: molecular docking; human tyrosinase; trigonelline; docking studies ... See more keywords

In Vitro Antileishmanial and Immune Modulation of Trigonelline Against Leishmania major

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recommendations! Published in 2024 at "Parasite Immunology"

DOI: 10.1111/pim.13076

Abstract: The mechanistic study of new pharmaceutical compounds is crucial for evaluating their efficacy, identifying potential side effects, and optimising drug formulations. This study aimed to investigate the mechanism of action of trigonelline on the promastigote… read more here.

Keywords: leishmania major; vitro antileishmanial; expression levels; trigonelline ... See more keywords