Articles with "trilaciclib monotherapy" as a keyword



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Abstract 6674: Single-dose trilaciclib monotherapy potentiates antitumor immunity in the neoadjuvant setting of triple-negative breast cancer by modulating the composition and effector function of peripheral immune cells

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-6674

Abstract: Intravenous administration of trilaciclib transiently arrests cyclin-dependent kinase 4/6-dependent cells in the G1 phase of the cell cycle during chemotherapy exposure. In an open-label, phase 2 study in patients with metastatic triple-negative breast cancer (TNBC;… read more here.

Keywords: single dose; trilaciclib; trilaciclib monotherapy; dose trilaciclib ... See more keywords