The protective effect of trilobatin against isoflurane-induced neurotoxicity in mouse hippocampal neuronal HT22 cells involves the Nrf2/ARE pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology"
DOI: 10.1016/j.tox.2020.152537
Abstract: Long-term exposure to isoflurane may induce long-term developmental neurotoxicity and cognitive impairments in the neonatal brains. Trilobatin, a leaf extract from the Chinese traditional sweet tea Lithocarpus polystachyus Rehd, possesses various biological properties including anti-inflammatory… read more here.
Keywords: ht22 cells; isoflurane induced; neurotoxicity; trilobatin ... See more keywords
Biosynthesis of the Dihydrochalcone Sweetener Trilobatin Requires Phloretin Glycosyltransferase2.
Sign Up to like & getrecommendations! Published in 2020 at "Plant physiology"
DOI: 10.1104/pp.20.00807
Abstract: Epidemics of obesity and type 2 diabetes drive strong consumer interest in plant-based low-calorie sweeteners. Trilobatin is a sweetener found at high concentrations in the leaves of a range of crabapple (Malus) species, but not… read more here.
Keywords: dihydrochalcone sweetener; sweetener; pgt2; trilobatin ... See more keywords