The role of TRIM family proteins in autophagy, pyroptosis, and diabetes mellitus
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11550
Abstract: The ubiquitin‐proteasome system, which is one of the systems for cell protein homeostasis and degradation, happens through the ordered and coordinated action of three types of enzymes, E1 ubiquitin‐activating enzyme, E2 ubiquitin‐carrier enzyme, E3 ubiquitin‐protein… read more here.
Keywords: autophagy pyroptosis; diabetes mellitus; role; trim family ... See more keywords
TRIM family proteins: roles in proteostasis and neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2022 at "Open Biology"
DOI: 10.1098/rsob.220098
Abstract: Neurodegenerative diseases (NDs) are a diverse group of disorders characterized by the progressive degeneration of the structure and function of the central or peripheral nervous systems. One of the major features of NDs, such as… read more here.
Keywords: roles proteostasis; trim family; proteins roles; family proteins ... See more keywords
Emerging Role of TRIM Family Proteins in Cardiovascular Disease
Sign Up to like & getrecommendations! Published in 2020 at "Cardiology"
DOI: 10.1159/000506150
Abstract: Ubiquitination is one of the basic mechanisms of cell protein homeostasis and degradation and is accomplished by 3 enzymes, E1, E2, and E3. Tripartite motif-containing proteins (TRIMs) constitute the largest subfamily of RING E3 ligases,… read more here.
Keywords: emerging role; role trim; disease; trim family ... See more keywords
Ubiquitination-coupled liquid phase separation regulates the accumulation of the TRIM family of ubiquitin ligases into cytoplasmic bodies
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0272700
Abstract: Many members of the tripartite motif (TRIM) family of ubiquitin ligases localize in spherical, membrane-free structures collectively referred to as cytoplasmic bodies (CBs) in a concentration-dependent manner. These CBs may function as aggresome precursors or… read more here.
Keywords: cytoplasmic bodies; family ubiquitin; trim family; ubiquitin ligases ... See more keywords
Emerging Roles of TRIM Family Proteins in Gliomas Pathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14184536
Abstract: Simple Summary Gliomas remain challenging tumors due to their increased heterogeneity, complex molecular profile, and infiltrative phenotype that are often associated with a dismal prognosis. In a constant search for molecular changes and associated mechanisms,… read more here.
Keywords: family; role; roles trim; trim family ... See more keywords
Genomic Analysis, Evolution and Characterization of E3 Ubiquitin Protein Ligase (TRIM) Gene Family in Common Carp (Cyprinus carpio)
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DOI: 10.3390/genes14030667
Abstract: Simple Summary TRIM family proteins form a large family of proteins that play a central role in antiviral host defense. These proteins are characterized and identified in tetrapods but the knowledge related to this family… read more here.
Keywords: family; ontology; trim family; analysis ... See more keywords
Positive Selection and Duplication of Bat TRIM Family Proteins
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DOI: 10.3390/v15040875
Abstract: Bats have received increasing attention because of some unique biological features they possess. TRIM is a large family of proteins that participate in diverse cellular functions, such as antiviral immunity, DNA damage repair, tumor suppression,… read more here.
Keywords: family; positive selection; trim family; family proteins ... See more keywords