Molecular and biological functions of TRIM‐NHL RNA‐binding proteins
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DOI: 10.1002/wrna.1620
Abstract: The TRIM‐NHL family of proteins shares a conserved domain architecture and play crucial roles in stem cell biology, fertility, and development. This review synthesizes new insights that have revolutionized our understanding of the molecular and… read more here.
Keywords: biological functions; rna; rna binding; trim nhl ... See more keywords
Comparative structural analyses of the NHL domains from the human E3 ligase TRIM–NHL family
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DOI: 10.1107/s2052252522008582
Abstract: Family-wide structural analyses of human TRIM NHL domains reveal evolutionary divergence of their β-propeller architecture that might be essential for recruiting diverse interacting partners and for the roles of NHL domains as E3 ligases. read more here.
Keywords: analyses nhl; structural analyses; family; trim nhl ... See more keywords
The TRIM-NHL protein NHL-2 is a co-factor in the nuclear and somatic RNAi pathways in C. elegans
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DOI: 10.7554/elife.35478
Abstract: Proper regulation of germline gene expression is essential for fertility and maintaining species integrity. In the C. elegans germline, a diverse repertoire of regulatory pathways promote the expression of endogenous germline genes and limit the… read more here.
Keywords: protein; nhl factor; trim nhl; germline ... See more keywords