TRIM proteins in blood cancers
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cell Communication and Signaling"
DOI: 10.1007/s12079-017-0423-5
Abstract: Post-translational modification of proteins with ubiquitin plays a central role in regulating numerous cellular processes. E3 ligases determine the specificity of ubiquitination by mediating the transfer of ubiquitin to substrate proteins. The family of tripartite… read more here.
Keywords: trim proteins; blood cancers; proteins blood;
TRIM proteins in neuroblastoma
Sign Up to like & getrecommendations! Published in 2019 at "Bioscience Reports"
DOI: 10.1042/bsr20192050
Abstract: Abstract Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. Outcome for children with high-risk NB remains unsatisfactory. Accumulating evidence suggests that tripartite motif (TRIM) family proteins express diversely in various human cancers… read more here.
Keywords: trim proteins; proteins neuroblastoma;
Altered Expression of TRIM Proteins-Inimical Outcome and Inimitable Oncogenic Function in Breast Cancer with Diverse Carcinogenic Hallmarks.
Sign Up to like & getrecommendations! Published in 2022 at "Current molecular medicine"
DOI: 10.2174/1566524022666220111122450
Abstract: Deregulation of ubiquitin-mediated degradation of oncogene products or tumor suppressors appears to be implicated in the genesis of carcinomas, according to new clinical findings. Conferring to recent research, some members of the tripartite motif (TRIM)… read more here.
Keywords: expression; breast cancer; many trim; trim proteins ... See more keywords
TRIM Proteins in Colorectal Cancer: TRIM8 as a Promising Therapeutic Target in Chemo Resistance
Sign Up to like & getrecommendations! Published in 2021 at "Biomedicines"
DOI: 10.3390/biomedicines9030241
Abstract: Colorectal cancer (CRC) represents one of the most widespread forms of cancer in the population and, as all malignant tumors, often develops resistance to chemotherapies with consequent tumor growth and spreading leading to the patient’s… read more here.
Keywords: promising therapeutic; trim proteins; colorectal cancer; trim8 ... See more keywords
Multifaceted Roles of TRIM Proteins in Colorectal Carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms21207532
Abstract: Colorectal cancer (CRC) is one of the most frequently diagnosed tumor in humans and one of the most common causes of cancer-related death worldwide. The pathogenesis of CRC follows a multistage process which together with… read more here.
Keywords: signaling pathways; multifaceted roles; trim proteins; roles trim ... See more keywords