Downregulation of tripartite motif protein 11 attenuates cardiomyocyte apoptosis after ischemia/reperfusion injury via DUSP1-JNK1/2.
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DOI: 10.1002/cbin.11716
Abstract: BACKGROUND Currently, the prevention of ischemic diseases such as myocardial infarction associated with ischemia/reperfusion (I/R) injury remains to be a challenge. Thus, this study was designed to explore the effects of tripartite motif protein 11… read more here.
Keywords: overexpression; trim11; apoptosis; dusp1 ... See more keywords
TRIM11 suppresses ferritinophagy and gemcitabine sensitivity through UBE2N/TAX1BP1 signaling in pancreatic ductal adenocarcinoma
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DOI: 10.1002/jcp.30346
Abstract: Gemcitabine is first‐line chemotherapy for pancreatic cancer, however, the development of resistance limits its effectiveness. The tripartite motif‐containing 11 (TRIM11) protein plays crucial roles in tumor development and undergoes auto‐polyubiquitination to promote interactions in selective… read more here.
Keywords: trim11; ferritinophagy gemcitabine; ube2n tax1bp1; pancreatic ductal ... See more keywords
The E3 Ubiquitin Ligase TRIM11 Facilitates Gastric Cancer Progression by Activating the Wnt/β-Catenin Pathway via Destabilizing Axin1 Protein
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DOI: 10.1155/2022/8264059
Abstract: Background Aberrant expression of tripartite motif 11 (TRIM11) and the Wnt/β-catenin pathway are essential for facilitating tumorigenesis and progression in multiple types of cancer. Aim To investigate the molecular changes linking the dysregulation of TRIM11… read more here.
Keywords: trim11; wnt catenin; progression; catenin ... See more keywords
TRIM11 Upregulation Contributes to Proliferation, Invasion, and EMT of Hepatocellular Carcinoma Cells
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DOI: 10.3727/096504016x14774897404770
Abstract: The tripartite motif-containing protein 11 (TRIM11), a member of the TRIM protein family, has attracted much attention because of its involvement in the development of the central nervous system. It has gained renewed focus because… read more here.
Keywords: hepatocellular carcinoma; emt; proliferation invasion; trim11 ... See more keywords