Nuclear localization signal in TRIM22 is essential for inhibition of type 2 porcine reproductive and respiratory syndrome virus replication in MARC-145 cells
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DOI: 10.1007/s11262-019-01691-x
Abstract: Porcine reproductive and respiratory syndrome virus (PRRSV) infection causes one of the most economically important swine diseases worldwide. Tripartite motif-containing 22 (TRIM22), a TRIM family protein, has been identified as a crucial restriction factor that… read more here.
Keywords: porcine reproductive; reproductive respiratory; trim22; replication ... See more keywords
Interferon-inducible TRIM22 contributes to maintenance of HIV-1 proviral latency in T cell lines.
Sign Up to like & getrecommendations! Published in 2019 at "Virus research"
DOI: 10.1016/j.virusres.2019.05.009
Abstract: The human immunodeficiency virus type-1 (HIV-1) establishes a state of latent infection in a small number of CD4+ T lymphocytes that, nonetheless, represent a major obstacle to viral eradication. We here show that Tripartite Motif-containing… read more here.
Keywords: latency; interferon inducible; cell lines; hiv ... See more keywords
TRIM22 inhibits endometrial cancer progression through the NOD2/NF-kB signaling pathway and confers a favorable prognosis
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DOI: 10.3892/ijo.2020.5004
Abstract: Endometrial cancer (EnC) is a malignant gynecological tumor commonly observed in developed countries, specifically among post-menopausal women. Although numerous patients with EnC receive promising prognoses, those with advanced or metastatic disease often have a poor… read more here.
Keywords: prognosis; progression; pathway; endometrial cancer ... See more keywords
FOXC1-mediated TRIM22 regulates the excessive proliferation and inflammation of fibroblast-like synoviocytes in rheumatoid arthritis via NF-κB signaling pathway
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DOI: 10.3892/mmr.2022.12820
Abstract: Rheumatoid arthritis (RA) is a common systemic autoimmune disorder of unknown etiology, which threatens public health. The regulatory role of tripartite motif-containing 22 (TRIM22) has been reported in multiple types of cancers and disease, but… read more here.
Keywords: signaling pathway; proliferation; rheumatoid arthritis; expression ... See more keywords