Expressions of Type I and III Interferons, Endogenous Retroviruses, TRIM28, and SETDB1 in Children with Respiratory Syncytial Virus Bronchiolitis
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DOI: 10.3390/cimb45020079
Abstract: Interferons (IFNs) and IFN-stimulated genes (ISGs) play essential roles for the control of viral infections. Their expression in infants with respiratory syncytial virus (RSV) bronchiolitis is poorly defined. Human endogenous retroviruses (HERVs) represent 8% of… read more here.
Keywords: syncytial virus; expression; bronchiolitis; rsv ... See more keywords
Enhanced Expression of Human Endogenous Retroviruses, TRIM28 and SETDB1 in Autism Spectrum Disorder
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DOI: 10.3390/ijms23115964
Abstract: Human endogenous retroviruses (HERVs) are relics of ancestral infections and represent 8% of the human genome. They are no longer infectious, but their activation has been associated with several disorders, including neuropsychiatric conditions. Enhanced expression… read more here.
Keywords: human endogenous; autism spectrum; spectrum disorder; enhanced expression ... See more keywords
Pregnancy Is Associated with Impaired Transcription of Human Endogenous Retroviruses and of TRIM28 and SETDB1, Particularly in Mothers Affected by Multiple Sclerosis
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DOI: 10.3390/v15030710
Abstract: Accumulating evidence highlights the pathogenetic role of human endogenous retroviruses (HERVs) in eliciting and maintaining multiple sclerosis (MS). Epigenetic mechanisms, such as those regulated by TRIM 28 and SETDB1, are implicated in HERV activation and… read more here.
Keywords: endogenous retroviruses; multiple sclerosis; trim28 setdb1; human endogenous ... See more keywords