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   Articles with "trim55" as a keyword



TRIM55 restricts the progression of hepatocellular carcinoma through ubiquitin-proteasome-mediated degradation of NF90

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recommendations! Published in 2024 at "Cell Death Discovery"

DOI: 10.1038/s41420-024-02212-y

Abstract: Hepatocellular carcinoma (HCC) is a prevalent malignant tumor worldwide. Tripartite motif containing 55 (TRIM55), also known as muscle-specific ring finger 2 (Murf2), belongs to the TRIM protein family and serves as an E3 ligase. Recently,… read more here.

Keywords: hcc; hepatocellular carcinoma; trim55; degradation nf90 ... See more keywords

1179A novel exonic variant in TRIM55 gene predisposes to heart failure

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recommendations! Published in 2019 at "European Heart Journal"

DOI: 10.1093/eurheartj/ehz748.0021

Abstract: Heart failure is a potentially lethal cardiac disorder. The genetic variants as well as the molecular signaling pathways accounting for the majority of the heritability of sporadic heart failure are unknown. Here, we screened for… read more here.

Keywords: heart; variant; trim55; heart failure ... See more keywords

P0024TRIPARTITE MOTIF-CONTAINING 55 (TRIM55) PARTICIPATES IN THE IMMUNE RESPONSE IN THE EXPERIMENTAL ANTI-THY1 GLOMERULONEPHRITIS

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recommendations! Published in 2020 at "Nephrology Dialysis Transplantation"

DOI: 10.1093/ndt/gfaa142.p0024

Abstract: Mesangial proliferative glomerulonephritis (MsPGN) is considered as an immune- related disease. In the previous study, tripartite motif family was reported to be closely related to immune regulation. Therefore, we performed a series of experiments in… read more here.

Keywords: trim55; primary rmcs; anti thy1; motif containing ... See more keywords

TRIM55 suppresses inflammatory response after spinal cord injury by accelerating the ubiquitination and degradation of TLR4

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recommendations! Published in 2025 at "Journal of Orthopaedic Surgery and Research"

DOI: 10.1186/s13018-025-05922-w

Abstract: Spinal cord injury (SCI) is a neurological disorder characterized by severe and often irreversible damage to the spinal cord, for which no effective treatments currently exist. Ubiquitination, a reversible post-translational modification, plays a critical role… read more here.

Keywords: spinal cord; degradation; cord injury; trim55 ... See more keywords