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   Articles with "trim65" as a keyword



Research and development prospects of TRIM65

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recommendations! Published in 2025 at "Journal of Cancer Research and Clinical Oncology"

DOI: 10.1007/s00432-025-06285-9

Abstract: Ubiquitination, the prevalent posttranslational modification, plays a crucial role in regulating protein function, localization, and degradation within cellular environments. As an E3 ubiquitin ligase, TRIM65 has been shown in various studies to facilitate the ubiquitination… read more here.

Keywords: research development; development prospects; research; prospects trim65 ... See more keywords

TRIM65 Promotes Malignant Cell Behaviors in Triple-Negative Breast Cancer by Impairing the Stability of LATS1 Protein

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/4374978

Abstract: TNBC is a malignant tumor that easily relapses and metastasizes, with a poor prognosis in women. Ubiquitination plays a key role in promoting the tumor process. In various tumors, TRIM65 can affect malignant biological tumor… read more here.

Keywords: promotes malignant; trim65; tnbc; lats1 protein ... See more keywords

TRIM65 Promotes Cervical Cancer Through Selectively Degrading p53-Mediated Inhibition of Autophagy and Apoptosis

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recommendations! Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.853935

Abstract: Tripartite motif containing 65 (TRIM65) is an E3 ubiquitin ligase that has been implicated in a variety of cellular processes as well as tumor progression, but its biological role and the underlying mechanism in cervical… read more here.

Keywords: cervical cancer; autophagy apoptosis; p53; trim65 ... See more keywords

Tripartite Motif-Containing Protein 65 (TRIM65) Inhibits Hepatitis B Virus Transcription

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recommendations! Published in 2024 at "Viruses"

DOI: 10.3390/v16060890

Abstract: Tripartite motif (TRIM) proteins, comprising a family of over 100 members with conserved motifs, exhibit diverse biological functions. Several TRIM proteins influence viral infections through direct antiviral mechanisms or by regulating host antiviral innate immune… read more here.

Keywords: hbv; hepatitis virus; tripartite motif; trim proteins ... See more keywords