Synthesis and Characterization of Propeller- and Parallel-Type Full-Length Amyloid β40 Trimer Models.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00363
Abstract: Oligomers of the amyloid β (Aβ) protein play a critical role in the pathogenesis of Alzheimer's disease. However, their heterogeneity and lability deter the identification of their tertiary structures and mechanisms of action. Aβ trimers… read more here.
Keywords: cytotoxicity; trimer; trimer models; propeller ... See more keywords