The collectin SP-A and its trimeric recombinant fragment protect alveolar epithelial cells from the cytotoxic and proinflammatory effects of human cathelicidin in vitro
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DOI: 10.3389/fimmu.2022.994328
Abstract: Human cathelicidin (LL-37) is a defense peptide with antimicrobial activity against various pathogens. However, LL-37 can also trigger tissue injury by binding to host cell membranes. The cytotoxic effects of LL-37 may be especially relevant… read more here.
Keywords: recombinant fragment; trimeric recombinant; rfhsp; human cathelicidin ... See more keywords