Cyclic ether synthesis from diols using trimethyl phosphate.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc01514c
Abstract: Cyclic ethers have been effectively synthesized via the intramolecular cyclization of diols using trimethyl phosphate and NaH. The present cyclization could proceed at room temperature to produce 5-7 membered cyclic ethers in good to excellent… read more here.
Keywords: trimethyl phosphate; using trimethyl; cyclic ether; cyclic ethers ... See more keywords
UHPLC-MS/MS Method Development and Validation for the Genotoxic Impurities Trimethyl Phosphate and Triisopropyl Phosphate of Elagolix Sodium.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of chromatographic science"
DOI: 10.1093/chromsci/bmad038
Abstract: Elagolix sodium is a gonadotropin-releasing hormone (GnRH) receptor antagonist that inhibits endogenous GnRH signaling by competitively binding to GnRH receptors in the pituitary gland to treat moderate to severe pain associated with endometriosis. To keep… read more here.
Keywords: triisopropyl phosphate; phosphate triisopropyl; elagolix sodium; genotoxic impurities ... See more keywords