Subtle sequence variations alter tripartite complex kinetics and G-quadruplex dynamics in RNA aptamer Broccoli.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/c9cc09375c
Abstract: Though extensively utilized, the fluorescent RNA aptamer Broccoli is poorly characterized with an unknown structure. Spectroscopic and kinetic investigations of tripartite complex formation reveal surprising differences between Broccoli and Spinach aptamers despite extreme sequence conservation.… read more here.
Keywords: subtle sequence; sequence variations; rna aptamer; tripartite complex ... See more keywords
Crystal structure of a tripartite complex between C3dg, C-terminal domains of factor H and OspE of Borrelia burgdorferi
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DOI: 10.1371/journal.pone.0188127
Abstract: Complement is an important part of innate immunity. The alternative pathway of complement is activated when the main opsonin, C3b coats non-protected surfaces leading to opsonisation, phagocytosis and cell lysis. The alternative pathway is tightly… read more here.
Keywords: c3dg; structure tripartite; tripartite complex; borrelia burgdorferi ... See more keywords
Mitochondrial Aurora kinase A induces mitophagy by interacting with MAP1LC3 and Prohibitin 2
Sign Up to like & getrecommendations! Published in 2021 at "Life Science Alliance"
DOI: 10.26508/lsa.202000806
Abstract: The multifunctional Ser/Thr kinase AURKA uses the Inner Mitochondrial Membrane receptor PHB2 and MAP1LC3 as a signalling platform to orchestrate the elimination of dysfunctional mitochondria. Epithelial and haematologic tumours often show the overexpression of the… read more here.
Keywords: kinase; phb2; inner mitochondrial; tripartite complex ... See more keywords