Unveiling a novel serpinB2/tripeptidyl peptidase II signaling axis during senescence.
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DOI: 10.1242/jcs.259513
Abstract: Tripeptidyl peptidase II (TPPII) degrades N-terminal tripeptides from proteins and peptides. Studies in both human and mice have shown that TPPII deficiency is linked to cellular immune-senescence, lifespan regulation, and the aging process. However, the… read more here.
Keywords: senescence; serpinb2; tripeptidyl peptidase; activity ... See more keywords