Articles with "triple class" as a keyword



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Real-world treatment patterns and outcomes of triple-class treated patients with multiple myeloma in the United States

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Published in 2022 at "Expert Review of Hematology"

DOI: 10.1080/17474086.2023.2154648

Abstract: ABSTRACT Objectives Although multiple myeloma (MM) survival has improved following the introduction of proteosome inhibitors, immunomodulatory drugs, and anti-CD38 therapies, patients become refractory to these agents. Real-world outcomes of triple-class exposed patients are limited and… read more here.

Keywords: exposure; outcomes triple; triple class; class ... See more keywords
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How I treat triple-class refractory multiple myeloma.

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Published in 2022 at "British journal of haematology"

DOI: 10.1111/bjh.18185

Abstract: Immunomodulatory imide drugs (IMiDs), proteasome inhibitors (PIs) and anti-CD38 monoclonal antibodies (MoAbs) are the pillars of modern multiple myeloma (MM) therapy. The prognosis of patients with MM that became refractory to these three classes (triple-class… read more here.

Keywords: multiple myeloma; triple class; class refractory;
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Carfilzomib, Cyclophosphamide, and Dexamethasone (KCd) for the Treatment of Triple-class Relapsed/Refractory Multiple Myeloma (RRMM).

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Published in 2021 at "European journal of haematology"

DOI: 10.1111/ejh.13697

Abstract: BACKGROUND Multiple myeloma (MM) is an incurable hematologic malignancy, and outcomes remain poor for patients with triple-class relapsed/refractory MM (RRMM). Descriptive analyses were performed on available data for patient characteristics, disease course, and outcomes of… read more here.

Keywords: relapsed refractory; class; triple class; multiple myeloma ... See more keywords
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Indirect treatment comparison of idecabtagene vicleucel versus conventional care in triple-class exposed multiple myeloma.

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Published in 2022 at "Journal of comparative effectiveness research"

DOI: 10.2217/cer-2022-0045

Abstract: Aim: To compare the efficacy of idecabtagene vicleucel (ide-cel, bb2121) versus conventional care (CC) in triple-class exposed relapsed and refractory multiple myeloma (RRMM) patients. Patients & methods: A matching-adjusted indirect comparison was conducted using individual… read more here.

Keywords: care triple; versus conventional; idecabtagene vicleucel; triple class ... See more keywords
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Practice patterns and outcomes for triple-class exposed patients with relapsed/refractory multiple myeloma in Japan.

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Published in 2022 at "Future oncology"

DOI: 10.2217/fon-2022-0846

Abstract: Aim: Treatment options for triple-class exposed (TCE) patients with multiple myeloma (MM) in Japan are limited. Materials & methods: Retrospective observational study using the Medical Data Vision database (April 2008-April 2021). Eligible adults with MM… read more here.

Keywords: triple class; myeloma japan; class exposed; treatment ... See more keywords
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Clinical Management of Triple-Class Refractory Multiple Myeloma: A Review of Current Strategies and Emerging Therapies

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Published in 2022 at "Current Oncology"

DOI: 10.3390/curroncol29070355

Abstract: Major progress has been made in the upfront treatment of multiple myeloma, but the disease ultimately relapses and leads to death in the vast majority of those afflicted. New treatment strategies and modalities are necessary… read more here.

Keywords: refractory; triple class; myeloma; treatment ... See more keywords