Fabrication of tumor-targeting composites based on the triple helical β-glucan through conjugation of aptamer.
Sign Up to like & getrecommendations! Published in 2021 at "Carbohydrate polymers"
DOI: 10.1016/j.carbpol.2020.117476
Abstract: Herein the nucleic acid aptamers were attached to the polydeoxyadenylic acid (poly(dA)) tail for improving the tumor-targetability and cellular internalization of s-LNT/poly(dA) composite composed of two single chains of triple helical β-glucan lentinan (s-LNT) and… read more here.
Keywords: helical glucan; lnt; poly; triple helical ... See more keywords
Experimental investigation on the VIV of two side-by-side risers fitted with triple helical strakes under coupled interference effect
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Fluids and Structures"
DOI: 10.1016/j.jfluidstructs.2020.103202
Abstract: Abstract Triple helical strakes have been proved to be highly effective in suppressing the vortex-induced vibration (VIV) of isolated riser. Nevertheless, when risers work in clusters, interference effect can give rise to more complicated flow-induced… read more here.
Keywords: effect; side side; helical strakes; triple helical ... See more keywords
The 2-Aminopyridine Nucleobase Improves Triple-Helical Recognition of RNA and DNA When Used Instead of Pseudoisocytosine in Peptide Nucleic Acids.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemistry"
DOI: 10.1021/acs.biochem.1c00275
Abstract: Pseudoisocytosine (J), a neutral analogue of protonated cytosine, is currently the gold standard modified nucleobase in peptide nucleic acids (PNAs) for the formation of J·G-C triplets that are stable at physiological pH. This study shows… read more here.
Keywords: peptide nucleic; rna dna; triple helical; nucleic acids ... See more keywords
The recognition mechanism of triple-helical β-1,3-glucan by a β-1,3-glucanase.
Sign Up to like & getrecommendations! Published in 2017 at "Chemical communications"
DOI: 10.1039/c7cc03330c
Abstract: β-1,3-Glucan is one of the most abundant polysaccharides in fungi. Recognition of β-1,3-glucan occurs in both hydrolysis by glycoside hydrolases and immunological recognition. Our study provides a novel structural account of how glycoside hydrolase recognizes… read more here.
Keywords: helical glucan; recognition mechanism; recognition; glucan glucanase ... See more keywords
Rules for the design of aza-glycine stabilized triple-helical collagen peptides†
Sign Up to like & getrecommendations! Published in 2020 at "Chemical Science"
DOI: 10.1039/d0sc03003a
Abstract: The stability of the triple-helical structure of collagen is modulated by a delicate balance of effects including polypeptide backbone geometry, a buried hydrogen bond network, dispersive interfacial interactions, and subtle stereoelectronic effects. Although the different… read more here.
Keywords: collagen; collagen peptides; geometry; helical collagen ... See more keywords
ABCG5 and ABCG8 gene variations associated with sitosterolemia and platelet dysfunction
Sign Up to like & getrecommendations! Published in 2020 at "Platelets"
DOI: 10.1080/09537104.2020.1779926
Abstract: Sitosterolemia (OMIM 210250) is a rare inherited autosomal recessive disorder of lipid metabolism, characterized by increased levels of plasma plant sterols (PS) such as stigmasterol, campesterol, and sitosterol [1,2]. Only around 100 patients with sitosterolemia… read more here.
Keywords: abcg5 abcg8; gene variations; tmd; abcg8 gene ... See more keywords