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   Articles with "triple mutant" as a keyword



Transformation of ε-HBCD with the Sphingobium Indicum enzymes LinA1, LinA2 and LinATM, a triple mutant of LinA2.

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recommendations! Published in 2020 at "Chemosphere"

DOI: 10.1016/j.chemosphere.2020.129217

Abstract: Hexabromocyclododecanes (HBCDs) were used as flame-retardants until their ban in 2013. Among the 16 stereoisomers known, ε-HBCD has the highest symmetry. This makes ε-HBCD an interesting substrate to study the selectivity of biotransformations. We expressed… read more here.

Keywords: lina2; hbcd; triple mutant; linatm triple ... See more keywords
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Triple-mutant AML: too clever by HLF?

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recommendations! Published in 2019 at "Blood"

DOI: 10.1182/blood.2019001533

Abstract: In this issue of Blood, Garg et al report on their investigation of the molecular interaction between mutations affecting DNMT3A and NPM1, and internal tandem duplications (ITDs) of FLT3 in acute myeloid leukemia (AML). They… read more here.

Keywords: aml clever; triple mutant; hlf; aml ... See more keywords
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Development of the triple-mutant oncolytic adenovirus for treatment of metastatic cancer by means of intravascular virus administration.

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recommendations! Published in 2018 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2018.36.15_suppl.e14546

Abstract: e14546Background: Oncolytic virotherapy of cancers is a rapidly growing new area of translational research and development that has the potential to improve treatment of currently incurable maligna... read more here.

Keywords: triple mutant; mutant oncolytic; treatment; oncolytic adenovirus ... See more keywords

ONT sequencing identifies a high prevalence of crt sensitive, triple mutant dhfr and single mutant dhps parasites within an ANC population in Nigeria

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recommendations! Published in 2024 at "Frontiers in Genetics"

DOI: 10.3389/fgene.2024.1470156

Abstract: Background Malaria in pregnancy is a major public health issue, particularly among vulnerable populations in malaria-endemic sub-Saharan African countries. To mitigate its risks, WHO recommends sulphadoxine-pyrimethamine (SP) for chemoprevention and artemisinin-based combination therapy (ACT) to… read more here.

Keywords: resistance; multiplexed amplicon; triple mutant; pregnant women ... See more keywords