SETDB1 activity is globally directed by H3K14 acetylation via its Triple Tudor Domain
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DOI: 10.1101/2024.04.22.590554
Abstract: SETDB1 is a major H3K9 methyltransferase involved in heterochromatin formation and silencing of repeat elements. It contains a unique Triple Tudor Domain (3TD) which specifically binds the dual modification of H3K14ac in the presence of… read more here.
Keywords: activity globally; setdb1; h3k14 acetylation; triple tudor ... See more keywords