A universal model of RNA.DNA:DNA triplex formation accurately predicts genome-wide RNA–DNA interactions
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in Bioinformatics"
DOI: 10.1093/bib/bbac445
Abstract: Abstract RNA.DNA:DNA triple helix (triplex) formation is a form of RNA–DNA interaction which regulates gene expression but is difficult to study experimentally in vivo. This makes accurate computational prediction of such interactions highly important in… read more here.
Keywords: dna interactions; rna dna; dna; triplex formation ... See more keywords
Modification of the aminopyridine unit of 2′-deoxyaminopyridinyl-pseudocytidine allowing triplex formation at CG interruptions in homopurine sequences
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gky704
Abstract: Abstract The antigene strategy based on site-specific recognition of duplex DNA by triplex DNA formation has been exploited in a wide range of biological activities. However, specific triplex formation is mostly restricted to homo-purine strands… read more here.
Keywords: inversion sites; inversion; aminopyridine unit; formation ... See more keywords