LNA effects on DNA binding and conformation: from single strand to duplex and triplex structures
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DOI: 10.1038/s41598-017-09147-8
Abstract: The anti-gene strategy is based on sequence-specific recognition of double-strand DNA by triplex forming (TFOs) or DNA strand invading oligonucleotides to modulate gene expression. To be efficient, the oligonucleotides (ONs) should target DNA selectively, with… read more here.
Keywords: lna effects; duplex triplex; effects dna; strand ... See more keywords