A Glucose-Triptolide Conjugate Selectively Targets Cancer Cells under Hypoxia
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DOI: 10.1016/j.isci.2020.101536
Abstract: Summary A major hurdle in the treatment of cancer is chemoresistance induced under hypoxia that is characteristic of tumor microenvironment. Triptolide, a potent inhibitor of eukaryotic transcription, possesses potent antitumor activity. However, its clinical potential… read more here.
Keywords: triptolide conjugate; cells hypoxia; antitumor activity; cancer cells ... See more keywords