Silk fibroin double-layer microneedles for the encapsulation and controlled release of triptorelin.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.121433
Abstract: A double-layer silk fibroin microneedles (SF-MNs) was proposed for the transdermal delivery of triptorelin. Two-step pouring and centrifugation were employed to prepare SF-MNs. Triptorelin was wrapped in MNs in the form of microcrystals with a… read more here.
Keywords: release; silk fibroin; triptorelin; double layer ... See more keywords
A single blood sample for stimulated LH assayed by ICMA is useful for monitoring the treatment efficacy of triptorelin depot in girls
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2022.2148120
Abstract: Abstract Background: There is still no consensus on the optimal monitoring method to evaluate the hypothalamic-pituitary-gonadal axis (HPGA) inhibition. Methods: There were 124 girls treated with triptorelin depot due to puberty disorders, including 77 central… read more here.
Keywords: treatment efficacy; triptorelin depot; triptorelin; monitoring ... See more keywords
Comparison of triptorelin acetate vs triptorelin pamoate in the treatment of Central precocious puberty (CPP): a retrospective study
Sign Up to like & getrecommendations! Published in 2019 at "Gynecological Endocrinology"
DOI: 10.1080/09513590.2019.1655726
Abstract: Abstract The aim of this study is to compare the clinical and biochemical outcomes of triptorelin acetate (TPA) versus triptorelin pamoate (TPP) treatment in girls with central precocious puberty. A total of 60 patients with… read more here.
Keywords: triptorelin; triptorelin pamoate; central precocious; treatment ... See more keywords
Radiosensitivity Enhancement using Triptorelin Conjugated Bismuth Sulfide Nanoparticles (Bi2S3@BSA) in Radiotherapy for Breast Cancer Cells
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Nanomaterials"
DOI: 10.1155/2023/5485632
Abstract: The aim of this study was to assess the radiosensitivity of bismuth sulfide nanoparticles conjugated with a synthetic agonist analog of gonadotropin-releasing hormones in targeted radiotherapy for breast cancer. After synthesis and characterization of nanoparticles,… read more here.
Keywords: bismuth sulfide; sulfide nanoparticles; triptorelin; bi2s3 bsa ... See more keywords
Pulmonary Delivery of Triptorelin Loaded in Pluronic Based Nanomicelles in Rat Model.
Sign Up to like & getrecommendations! Published in 2018 at "Current drug delivery"
DOI: 10.2174/1567201815666180209113735
Abstract: INTRODUCTION Triptorelin, the synthetic analog of gonadotrophin-releasing hormone, is used for the treatment of sex hormone dependent diseases via parenteral administration. The aim of the present study was to investigate the possibility of triptorelin pulmonary… read more here.
Keywords: triptorelin; pulmonary delivery; delivery; solution ... See more keywords
Leuprolide and triptorelin treatment in children with idiopathic central precocious puberty: an efficacy/tolerability comparison study
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Pediatrics"
DOI: 10.3389/fped.2023.1170025
Abstract: Introduction Central precocious puberty (CPP) results from premature activation of hypothalamic-pituitary-gonadal axis, with the consequent increase of gonadotropin-releasing hormone (GnRH); GnRH agonists (GnRHa) represent the gold-standard therapy in children with CPP although their use might… read more here.
Keywords: triptorelin; efficacy tolerability; study; leuprolide triptorelin ... See more keywords