Development of Phloroglucinol-Linked Tris-Quaternary Ammonium Salt Antimicrobial Peptide Mimics with Low Cytotoxicity and Broad-Spectrum Antibacterial Activity.
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DOI: 10.1021/acs.jmedchem.4c01935
Abstract: Encouraged by the significantly different toxicities and antibacterial activities of diverse linkers, such as alkyl and aromatic nuclei linkers, and the unique structure of phloroglucinol, we synthesized a series of tris-quaternary ammonium salt (tris-QAS) antibacterial… read more here.
Keywords: tris quaternary; ammonium salt; phloroglucinol; quaternary ammonium ... See more keywords