The impact of proline isomerization on antigen binding and the analytical profile of a trispecific anti-HIV antibody
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DOI: 10.1080/19420862.2019.1698128
Abstract: ABSTRACT Proline cis-trans conformational isomerization is a mechanism that affects different types of protein functions and behaviors. Using analytical characterization, structural analysis, and molecular dynamics simulations, we studied the causes of an aberrant two-peak size-exclusion… read more here.
Keywords: hiv antibody; antibody; isomerization; trispecific anti ... See more keywords