Articles with "trisubstituted imidazole" as a keyword



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An efficient and eco-compatible multicomponent synthesis of 2,4,5-trisubstituted imidazole derivatives using modified-silica-coated cobalt ferrite nanoparticles with tungstic acid.

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Published in 2023 at "Dalton transactions"

DOI: 10.1039/d2dt03021g

Abstract: The aim of this study has been to offer a method for the synthesis of 2,4,5-trisubstituted imidazole derivatives based on green chemistry principles. Therefore, a one-pot multicomponent cyclocondensation reaction through aldehyde interaction with ammonium acetate… read more here.

Keywords: synthesis trisubstituted; efficient eco; imidazole derivatives; tungstic acid ... See more keywords

3D-QSAR modeling and molecular docking studies on a series of 2, 4, 5-trisubstituted imidazole derivatives as CK2 inhibitors

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Published in 2022 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2021.2014360

Abstract: Abstract Protein case in kinase II alpha subunit (CK2) plays an imperative function in treating cancer disease. Herein, we have performed a three-dimensional quantitative structure activity relationship (3D-QSAR), and molecular docking analysis on a novel… read more here.

Keywords: molecular docking; series trisubstituted; imidazole derivatives; analysis ... See more keywords