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Synthesis of Novel 1-Oxo-2,3,4-trisubstituted Tetrahydroisoquinoline Derivatives, Bearing Other Heterocyclic Moieties and Comparative Preliminary Study of Anti-Coronavirus Activity of Selected Compounds

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Published in 2023 at "Molecules"

DOI: 10.3390/molecules28031495

Abstract: A series of novel 1-oxo-2,3,4-trisubstituted tetrahydroisoquinoline (THIQ) derivatives bearing other heterocyclic moieties in their structure were synthesized based on the reaction between homophthalic anhydride and imines. Initial studies were carried out to establish the anti-coronavirus… read more here.

Keywords: trisubstituted tetrahydroisoquinoline; bearing heterocyclic; novel oxo; oxo trisubstituted ... See more keywords