TRITON3: An international, randomized, open-label, phase III study of the PARP inhibitor rucaparib vs. physician’s choice of therapy for patients with metastatic castration-resistant prostate cancer (mCRPC) associated with homologous recombination deficiency (HRD).
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DOI: 10.1200/jco.2018.36.6_suppl.tps389
Abstract: TPS389Background: Recent data have shown that up to 25% of patients with advanced prostate cancer, including mCRPC, have a deleterious germline or somatic mutation in BRCA1, BRCA2, ATM, or another ... read more here.
Keywords: open label; randomized open; prostate cancer; international randomized ... See more keywords