Orexin A injection into the ventral medial prefrontal cortex induces antidepressant-like effects: Possible involvement of local Orexin-1 and Trk receptors
Sign Up to like & getrecommendations! Published in 2020 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2020.112866
Abstract: RATIONALE Reduced levels of orexin-A (OXA) in the central nervous system (CNS) have been associated with the pathophysiology of depression and its exogenous administration promotes antidepressant-like effect. The mechanisms associated with these effects are, however,… read more here.
Keywords: induces antidepressant; trk receptors; vmpfc; antidepressant like ... See more keywords
Trk Receptors and Neurotrophin Cross-Interactions: New Perspectives Toward Manipulating Therapeutic Side-Effects
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2017.00130
Abstract: Some therapeutic side-effects result from simultaneous activation of homolog receptors by the same ligand. Tropomyosin receptor kinases (TrkA, TrkB and TrkC) play a major role in the development and biology of neurons through neurotrophin signaling.… read more here.
Keywords: cross interactions; side effects; therapeutic side; trk receptors ... See more keywords
Localization of Neurotrophin Specific Trk Receptors in Mechanosensory Systems of Killifish (Nothobranchius guentheri)
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DOI: 10.3390/ijms221910411
Abstract: Neurotrophins (NTs) and their signal-transducing Trk receptors play a crucial role in the development and maintenance of specific neuronal subpopulations in nervous and sensory systems. NTs are supposed to regulate two sensory systems in fish,… read more here.
Keywords: mechanosensory systems; inner ear; trk receptors; trk ... See more keywords
RET receptor expression and interaction with TRK receptors in neuroblastomas.
Sign Up to like & getrecommendations! Published in 2020 at "Oncology reports"
DOI: 10.3892/or.2020.7583
Abstract: Neuroblastomas (NBs) have heterogeneous clinical behavior, from spontaneous regression or differentiation to relentless progression. Evidence from our laboratory and others suggests that neurotrophin receptors contribute to these disparate behaviors. Previously, the role of TRK receptors… read more here.
Keywords: receptor expression; gfr; trk receptors; trk ... See more keywords